High-flux haemodialysis treatment as treatment for carbamazepine intoxication.
نویسندگان
چکیده
Acute severe intoxication with carbamazepine is associated with seizures, coma and respiratory depression. Traditionally, charcoal haemoperfusion is used to remove the drug. We present a case of carbamazepine intoxication, successfully treated with three hours of high-flux haemodialysis. Thus, haemodialysis using high-flux membranes is a feasible and effective therapeutic option for carbamazepine intoxication.
منابع مشابه
Treatment of Severe Carbamazepine Intoxication with Intravenous Lipid Emulsion Therapy
Carbamazepine (CBZ) is a widely prescribed anticonvulsant agent. It is used in treatment of epilepsy including general tonic-clonic, simple partial and complex partial seizures, neuropathicpains, especially in trigeminalneuralgia, central diabetes insipidus, attention-deficit and hyperactivity disorders and bipolar disorders. CBZ overdose is usually associated with cardiac, neurologic and respi...
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BACKGROUND Although urea clearance is often increased during high-efficiency and high-flux haemodialysis to compensate for short treatment times, the impact of these treatment modalities on the removal of larger uraemic toxins has not been thoroughly investigated. METHODS We compared solute removal rates for five haemodialysis treatment strategies in vitro using neutral dextrans (molecular ra...
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carbamazepine are very similar to the clinical features of water intoxication. Dizziness, headaches, nausea, and mental confusion may occur with both, although it is not known what proportion of patients who develop these side effects on carbamazepine do so because of a fall in the plasma osmolality. When untoward symptoms develop during treatment and subside after the dose is reduced the mecha...
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Carbamazepine has recently been shown to have a vasopressin-like action and, like chlorpropamnide, to be effective in controlling polyuria in patients with diabetes insipidus (Hartman, 1972; Uhlich et al., 1972). In the case reported here carbamazepine, which was being given to a patient suffering from depression and psychogenic polydipsia, induced inappropriate secretion of antidiuretic hormon...
متن کاملWhich is the best in carbamazepine overdose?
Intravenous lipid emulsion treatment is safer, faster, and easier to apply and could be a powerful alternative to extracorporeal treatment methods in carbamazepine intoxication.
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ورودعنوان ژورنال:
- The Medical journal of Malaysia
دوره 61 1 شماره
صفحات -
تاریخ انتشار 2006